A Probable Approval of Ketamine in the Treatment of Depression
Really soon, ketamine may be approved as for medical treatment just as marijuana is in some countries. Ketamine has been used for medical purposes even when its use became illegal since people started using it as a recreational drug. Nowadays, ketamine may be approved for use in the treatment of depression.
Ketamine was used for the first time in 1962 as a treatment against chronic pains and anesthesia. In the 70s, ketamine was used as a drug. In the 90s, it was extremely popular among the visitors of the dance clubs because of its dissociative and hallucinatory effects.
The effect of ketamine does not last long, but it has been connected with deaths in traffic accidents as well as with drowning. In combination with other drugs, it can significantly raise your blood pressure.
Due to the deaths caused by ketamine consumption, there are many campaigns against ketamine. Nowadays, researchers are proving ketamine’s effectiveness as an antidepressant.
Recently, the Canadian Matthew Cooper published a review of all the repots which studied the effects of ketamine in the treatment of depression. Even though, all the studies separately are individual cases and small trial, together they present a powerful evidence of the effectiveness of ketamine in the treatment of depression.
The benefits of ketamine that are reported are very dramatic. For instance, Dennis Hartman suffered from severe and long-lasting depression. The trial with ketamine was the last chance for Hartman. In an interview in The Washington Post, Hartman explained that he divides his life before and after the first ketamine infusion. Even with the first infusion, this man felt how his pain and suffering are slowly ending. He was extremely joyful as the pain disappeared.
The ketamine use in the small trials is different from the use of ketamine by partygoers and the use of it in anesthetics. Nowadays, intranasal use of ketamine is the best way to mitigate psychotomimetic and dissociative effects. In other trials, intravenous drips are used. The dose of ketamine is also lower than the dose used before a surgery.
According to reported cases, these kinds of uses of ketamine have immediate positive effect. On the other side, the antidepressants that are used today need several weeks or even months to be effective and improve the mood. Sometimes, they may even be completely ineffective. Moreover, when the ketamine drug is eliminated, its positive effects remain for a long time.
The scientists know how the ketamine works in the treatment of depression, which is not the case with some other alternative treatments for depression. The glutamate receptors that are involved in depression are N-methyl-D-aspartate. Ketamine blocks these receptors and the receptors are not able to cause overstimulation of the cells in the brain.
The psychiatric associations in American have decided to consider ketamine in the treatment of PTSD and depression after seeing the evidence for ketamine’s effectiveness. Even though small doses of ketamine can cause dissociative state and hallucinations, addiction or serious damage if ketamine is used for treatment in controlled conditions is not possible.
The supporters of ketamine hope that the APA will soon approve the ketamine treatment trials despite the drug’s image and the legal issues that exist, since ketamine’s potential must be used.